Andreas Hoeflich Selected Research

Insulin-Like Growth Factor Binding Protein 2

1/2020	Reduced Fragmentation of IGFBP-2 and IGFBP-3 as a Potential Mechanism for Decreased Ratio of IGF-II to IGFBPs in Cerebrospinal Fluid in Response to Repeated Intrathecal Administration of Triamcinolone Acetonide in Patients With Multiple Sclerosis.
1/2020	Overlap of Peak Growth Activity and Peak IGF-1 to IGFBP Ratio: Delayed Increase of IGFBPs versus IGF-1 in Serum as a Mechanism to Speed up and down Postnatal Weight Gain in Mice.
12/2016	Role of PTHrP(1-34) Pulse Frequency Versus Pulse Duration to Enhance Mesenchymal Stromal Cell Chondrogenesis.
10/2015	Physiology and pathophysiology of IGFBP-1 and IGFBP-2 - consensus and dissent on metabolic control and malignant potential.
6/2015	Gender-specific effects on food intake but no inhibition of age-related fat accretion in transgenic mice overexpressing human IGFBP-2 lacking the Cardin-Weintraub sequence motif.
1/2014	Control of IGFBP-2 Expression by Steroids and Peptide Hormones in Vertebrates.
5/2009	IGFBP-2 overexpression reduces the appearance of dysplastic aberrant crypt foci and inhibits growth of adenomas in chemically induced colorectal carcinogenesis.
8/2006	IGF-independent effects of IGFBP-2 on the human breast cancer cell line Hs578T.
11/2002	Insulin-like growth factor binding protein 2 (IGFBP-2) separates hypertrophic and hyperplastic effects of growth hormone (GH)/IGF-I excess on adrenocortical cells in vivo.

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Andreas Hoeflich Research Topics

Disease

9	Neoplasms (Cancer) 10/2015 - 02/2002
6	Body Weight (Weight, Body) 01/2018 - 01/2007
4	Obesity 12/2020 - 01/2013
4	Carcinogenesis 01/2014 - 02/2002
4	Colorectal Neoplasms (Colorectal Cancer) 12/2010 - 03/2004
3	Hypertrophy 12/2016 - 11/2002
2	Genetic Predisposition to Disease (Genetic Predisposition) 01/2021 - 01/2016
2	Wounds and Injuries (Trauma) 12/2020 - 06/2004
2	Cardiovascular Diseases (Cardiovascular Disease) 12/2020 - 01/2018
2	Multiple Sclerosis 01/2020 - 01/2020
2	Inflammation (Inflammations) 01/2018 - 01/2017
2	Hypoglycemia (Reactive Hypoglycemia) 01/2018 - 06/2011
2	Atherosclerosis 01/2018 - 07/2003
2	Breast Neoplasms (Breast Cancer) 10/2015 - 08/2006
2	Aberrant Crypt Foci 12/2010 - 05/2009
2	Adenoma (Adenomas) 05/2009 - 02/2002
2	Colonic Neoplasms (Colon Cancer) 05/2009 - 01/2004
1	Weight Gain 01/2020
1	Encephalomyelitis (Myeloencephalitis) 01/2020
1	Laron Syndrome (Syndrome, Laron) 01/2018
1	Coronary Disease (Coronary Heart Disease) 01/2018
1	Fetal Growth Retardation (Intrauterine Growth Retardation) 01/2018
1	Lung Diseases (Lung Disease) 01/2017
1	Exsanguination 01/2017
1	Acute-Phase Reaction 01/2016
1	Fatty Liver 01/2016
1	Insulin Resistance 10/2015
1	Prostatic Neoplasms (Prostate Cancer) 10/2015
1	Ovarian Neoplasms (Ovarian Cancer) 10/2015
1	Glucose Intolerance 08/2015
1	Endotoxemia 01/2015
1	Sepsis (Septicemia) 01/2015
1	Atrophy 05/2014
1	Spinal muscular atrophy with respiratory distress 1 05/2014
1	Brain Neoplasms (Brain Tumor) 01/2014
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 07/2013
1	Rett Syndrome (Rett's Disorder) 07/2013
1	Hyperlipidemias (Hyperlipidemia) 05/2013
1	Abdominal Obesity 05/2013
1	Disease Progression 09/2012
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 09/2012
1	Motor Neuron Disease (Primary Lateral Sclerosis) 09/2012
1	Muscular Dystrophies (Muscular Dystrophy) 04/2012
1	Fatigue 04/2012
1	Myotonic Dystrophy (Dystrophia Myotonica) 01/2012

Drug/Important Bio-Agent (IBA)

10	Insulin-Like Growth Factor I (IGF-1)IBA 01/2020 - 11/2002
9	Insulin-Like Growth Factor Binding Protein 2IBA 01/2020 - 11/2002
8	Insulin-Like PeptidesIBA 01/2020 - 03/2004
5	Insulin-Like Growth Factor Binding ProteinsIBA 01/2020 - 06/2008
4	Insulin-Like Growth Factor II (Somatomedin A)IBA 01/2020 - 02/2002
4	Glucose (Dextrose)FDA LinkGeneric 01/2016 - 01/2013
3	Triglycerides (Triacylglycerol)IBA 01/2018 - 05/2013
3	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 05/2014 - 04/2012
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2012 - 02/2002
3	1,2-Dimethylhydrazine (1,2 Dimethylhydrazine)IBA 12/2010 - 11/2006
2	Messenger RNA (mRNA)IBA 01/2021 - 01/2016
2	Insulin-Like Growth Factor Binding Protein 3IBA 01/2020 - 01/2017
2	Triamcinolone Acetonide (Azmacort)FDA LinkGeneric 01/2020 - 01/2020
2	CholesterolIBA 01/2018 - 05/2013
2	Insulin (Novolin)FDA Link 10/2015 - 12/2010
2	Carrier Proteins (Binding Protein)IBA 05/2014 - 01/2007
2	polyethylene glycol(B1)- insulinIBA 09/2012 - 04/2012
2	Growth Hormone (Somatotropin)IBA 08/2009 - 06/2004
2	Dimenhydrinate (DMH)FDA LinkGeneric 05/2009 - 11/2006
1	Biomarkers (Surrogate Marker)IBA 01/2018
1	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 01/2018
1	Peptide Hydrolases (Proteases)FDA Link 01/2018
1	CytokinesIBA 01/2018
1	Protease Inhibitors (Protease Inhibitor)IBA 01/2018
1	Somatotropin Receptors (Growth Hormone Receptor)IBA 01/2018
1	Pregnancy-Associated Plasma Protein-A (PAPP-A)IBA 01/2017
1	Interleukin-6 (Interleukin 6)IBA 01/2017
1	Proteins (Proteins, Gene)FDA Link 12/2016
1	MicroRNAs (MicroRNA)IBA 12/2016
1	Parathyroid Hormone-Related ProteinIBA 12/2016
1	Sterol Regulatory Element Binding ProteinsIBA 01/2016
1	Fibrinogen (Factor I)FDA Link 01/2016
1	Progesterone FDA LinkGeneric 01/2016
1	SteroidsIBA 10/2015
1	Estrogens (Estrogen)FDA Link 10/2015
1	Insulin-Like Growth Factor Binding Protein 1IBA 10/2015
1	LeptinIBA 10/2015
1	EndotoxinsIBA 01/2015
1	Tryptophan (L-Tryptophan)FDA Link 01/2015
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2015
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2015
1	EnzymesIBA 01/2015
1	KynurenineIBA 01/2015
1	indolamineIBA 01/2015
1	Immunoglobulins (Immunoglobulin)IBA 05/2014
1	ElementsIBA 01/2014
1	Methyl-CpG-Binding Protein 2IBA 07/2013
1	3' Untranslated Regions (3' UTR)IBA 01/2012
1	Myotonin-Protein KinaseIBA 01/2012
1	Insulin Glargine (Lantus)FDA Link 12/2010
1	Bromodeoxyuridine (BrdU)IBA 12/2010

Therapy/Procedure

1	Therapeutics 12/2020
1	Resistance Training 12/2020
1	Spinal Injections 01/2020
1	Injections 04/2012